5-Amino-1MQ 5 mg is a small-molecule NNMT inhibitor supplied for laboratory research only. It is studied in models of high-fat-diet-induced obesity and metabolic syndrome, where it reduces NNMT enzyme activity and raises NAD+ levels.
- Function: Inhibits NNMT, a metabolic target in obesity and diabetes research.
- Mechanism: Increases NAD+ levels in laboratory models.
- Application: Studied in models of energy expenditure and body weight.
NNMT Inhibition
5-Amino-1MQ is a small, cell-permeable molecule that selectively inhibits nicotinamide N-methyltransferase (NNMT), an enzyme found primarily in fat tissue that influences energy metabolism. Inhibiting NNMT raises intracellular NAD+ levels, which are central to cellular energy production. It is studied for effects on fat metabolism and adipocyte biology in laboratory models.
Muscle Research
Preclinical work has examined how lowering NNMT activity affects muscle fibre regeneration and contractility, including in models of caloric restriction and exercise.
NAD+ and Longevity Research
NNMT levels increase with age and deplete NAD+, which is linked to reduced mitochondrial function in cellular ageing models. 5-Amino-1MQ is studied for its effect on NAD+ levels, mitochondrial function and cellular repair pathways in research on age-related metabolic decline.
Other Research Areas
Preclinical work has also examined its effects on metabolic markers such as cholesterol and insulin sensitivity, and on neural resilience to metabolic stress.
Quality and Storage
This 5 mg vial is produced to high purity standards through molecular synthesis and supplied lyophilised (freeze-dried) to maintain structural stability. Store in a cool, dark place or refrigerate at 2°C to 8°C, away from moisture and direct sunlight.
For laboratory and research purposes only. Not for human consumption, medical use, or veterinary use.
